Do You Know All 17 Of The Most Toxic Reagents In The Lab（3-6）
2023-03-14
3. DEPCDEPC (diethylprocarbonate), which can inactivate various proteins, is a strong inhibitor of RNA enzyme. DEPC is a potential carcinogen. It should be performed in ventilated conditions and avoid contact with skin.DEPC is not very toxic, but inhalation is the most toxic, wear a mask when using. Wash away immediately. RNase AwayTM is an easy, inexpensive and non-toxic alternative to DEPC. Simply pour RNaseAwayTM directly onto the surface of glassware and plastic ware and rinse away with water after soaking. The RNase can be quickly removed from the surface of the ware without remaining and interfering with subsequent experiments.4. AcrylamideIt is a moderately toxic substance that can be absorbed through the skin and enter the human body through the respiratory tract. Therefore, you must wear protective equipment during handling and use, such as respirator suit, respirator mask and respirator gloves. The harm of acrylamide is mainly caused by the toxicity of god, but also reproductive, developmental toxicity.Neurotoxic effects are manifested by peripheral neurodegenerative changes and degenerative changes in parts of the brain involved in learning, memory and other cognitive functions. Tests have also shown that acrylamide is a possible carcinogen. Epidemiological observations in occupational exposed populations have shown that long-term low dose exposure to acrylamide can cause symptoms such as drowsiness, changes in mood and memory, hallucinations and tremors. Accompanied by peripheral neuropathy like a glove sensation, sweating, and muscle weakness. Cumulative toxicity, not easy to detox.Anyone who has any of the following can be listed as the object of observation for chronic acrylamide poisoning.a. The local skin exposed to acrylamide appears sweaty, damp and cold, peeling and erythema;b. Symptoms of extremity numbness, tingling, lower limb weakness, lethargy, etc.;c. Neuro-electromyography shows suspicious neurogenic lesion.5. Nn-methyl-diacrylamideToxic, affects the central nervous system, do not inhale the powder.6.DTTdithiothreitolA very strong reducing agent with an unpleasant odor. Can be hazardous to health by inhalation, ingestion or skin absorption. When using solid or high concentration storage solution, wear gloves and goggles and operate in a fume hood.
A Week To Learn Knowledge Of 100 Q | Hazardous Chemical Materials Safety Management(2)
2023-03-07
Q:What is dangerous production "four strictly prohibited"?Answer: It is strictly prohibited to change the production variety at will; It is strictly prohibited to change the technology at will;It is strictly prohibited to rush the construction period and surprise production; Risky operation is strictly prohibited.Q:What is the "three is the same"?Answer: No cross operation is allowed; Remove all combustible materials on site; All combustible gas content shall be detected.
Into Learning The Breathtaking Chemistry The Most Of The World
3. The latest heaviest elementCalifornia in January 1991, Lawrence livermore Moore national laboratory and dubna, Russia's nuclear scientists who study union college, that found the heaviest elements may be the world's newest ð « § 1 elements The element contains 114 protons and is said to be more stable than other superheavy atoms. The element is produced when calcium isotopes bombard neutron-rich plutonium isotopes.4. The most acidic solutionStrong acid and base solutions tend to have Ph values of 0 and 14 respectively, but it is far from sufficient to use this value as a standard for describing "strong acids". The strongest of the strong acids is the fluoric acid with 80% solution of antimony fluoride 5. The acidity of this acidic solution has not been determined, but even the slightly weaker solution of 50% solution is 1018 times more acidic than the concentrated sulfuric acid solution.
Do You Know All 17 Of The Most Toxic Reagents In The Lab（two）
EB: EB (Ethidium bromide, bromide)Ethidium bromide is a highly sensitive fluorescent stain used to observe DNA in agarose and polyacrylamide gels. Ethidium bromide The most common way to observe DNA in agarose gels is to stain them with the fluorescent dye ethidium bromide, which contains a tricyclic plane group that can be embedded between the DNA's accumulated bases. Ethidium bromide is a strong mutagenic agent with high carcinogenicity! It will evaporate at 60-70 ° C (so it is best not to add it when the glue is too hot, or it should be added to the liquid, 0.5ug/ml, dyeing for half an hour) (When excessive EB is added, the dyed gel can also be soaked in water at room temperature for 20min to reduce the background fluorescence caused by unbound EB).Purification treatment of ethidium bromide solution: Because ethidium bromide has certain toxicity, after the end of the experiment, the solution containing EB should be purified and disposed of to avoid environmental pollution and harm to human health.(1) For the solution with EB content greater than 0.5mg/ml, it can be treated as follows:① Dilute EB solution with water to a concentration less than 0.5mg/ml;② Add 0.5mol/L KMnO4, mix well, then add an equal amount of 25mol/L HCl, mix well, and leave at room temperature for several hours;③ Add 2.5mol/L NaOH of one time volume, mix well and discard.(2) The solution with EB content less than 0.5mg/ml can be treated as follows:①Add activated carbon at the dosage of 1mg/ml, shake and mix gently from time to time, and place at room temperature for 1 hour;② Filter with filter paper and seal the activated carbon with filter paper before discarding.
Do You Know All 17 Of The Most Toxic Reagents In The Lab（one）
2023-03-06
1. DMSODMSO is a dimethyl sulfoxide, which is widely used. Used as a solvent for acetylene, aromatics, sulfur dioxide and other gases and as a spinning solvent for acrylic fibers. It is an important aprotic polar solvent soluble in both water and organic solvents. It is highly permeable to the skin and helps the drug penetrate into the human body. It can also be used as an additive to pesticides. It's also a very important chemical.DMSO is also an osmotic protector, which can reduce the freezing point of cells, reduce the formation of ice crystals, reduce free radical damage to cells, and change the permeability of biofilms to electrolytes, drugs, poisons and metabolites.However, studies have shown that DMSO has serious toxic effects, interacting with protein hydrophobic groups, leading to protein denaturation, vascular toxicity and hepatorenal toxicity.DMSO is a highly toxic substance, so it should be avoided from volatilization when used. 1%-5% ammonia water should be prepared for reserve, and the skin should be washed with a lot of water and dilute ammonia water after being stained. The most common are nausea, vomiting, skin rashes, and garlic, onion, and oyster smells on the skin and exhaled gas.Inhalation: High volatile concentrations may cause headache, dizziness and sedation.Skin: Can burn and tingle the skin, as seen in rashes and blisters. Dimethyl sulfoxide produces a thermal reaction if it comes into contact with hydrated skin. Avoid contact with dimethyl sulfoxide solution containing toxic raw materials or substances, because its toxicity is not known, but dimethyl sulfoxide may penetrate the skin, under certain conditions will replace toxic substances into the skin.Absorption: Absorption risk is very low.
A Day To Learn Knowledge Of 100 Q | Hazardous Chemical Materials Safety Management(1)
Q:What is the "three is the same"?Answer: No cross operation is allowed; Remove all combustible materials on site; All combustible gas content shall be detected.
Into Learning The Breathtaking Chemistry The Most Of The World （one）
Nanping Jianyang Xinsheng Trading Co., LTD. Published in Fujian on February 20, 20231.The largest scientific instrument is the Large Positron (LEP) storage ring located in Siern, Geneva, Switzerland, with a circumference of 27 km. The ring itself is 3.8 meters in diameter. More than 60,000 tons of scientific instruments are housed in the pipeline and in eight work zones.2. The end of the scanning tunneling microscope probe is a single atom that makes up the last three layers of the world's smallest man-made pyramid: seven atoms, three atoms and one atom. In January 1990, scientists at the IBM Almorden Research Center in SAN Jose, California, announced that they had used a scanning tunneling microscope to move and rearrange individual atoms on the surfaces of xenon and nickel to spell out their company's initials: IBM. Other LABS have done this with individual atoms of other elements.
